WebThrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. This results in a low platelet count, low red blood cells due to their breakdown, and often kidney, heart, and brain dysfunction. Symptoms may include large bruises, fever, weakness, shortness of breath, confusion, …
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WebJul 10, 2014 · Thrombotic thrombocytopenic purpura (TTP) is an acute, rare, potentially life-threatening disorder, presenting with thrombocytopenia, hemolytic anemia, and clinical consequences of microvascular thrombosis, caused by deficiency of ADAMTS13. 1,2 The majority of acute cases are acquired, autoantibody mediated, and characterized by low … WebMay 25, 2024 · Practice Essentials. Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder characterized by clotting in small blood vessels (thromboses), resulting in a low platelet count. [ 1] In its full-blown form, the disease consists of the following pentad: Microangiopathic hemolytic anemia. Thrombocytopenic purpura. Neurologic abnormalities. sheppard tx zip code
Thrombotic thrombocytopenic purpura - MedlinePlus
WebMar 24, 2024 · This may cause bleeding and bruising. “Thrombotic” refers to the blood clots that form. “Thrombocytopenic” means the blood has a lower-than-normal platelet count. … WebFeb 2, 2024 · Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy characterized by microangiopathic hemolytic anemia, severe thrombocytopenia, and ischemic end organ injury due to microvascular platelet-rich thrombi. TTP results from a severe deficiency of the specific von Willebrand fa … WebThrombotic thrombocytopenic purpura (TTP) is a blood disorder in which platelet clumps form in small blood vessels. This leads to a low platelet count (thrombocytopenia). Causes. This disease may be caused by problems with an enzyme (a type of protein) that is involved in blood clotting. springfield government model scope