WebTrimethoprim-Induced Hyperkalemia. Trimethoprim and pentamidine cause hyperkalemia by blocking ENaCs in the CCD. 58 Although frequently reported in patients who have acquired immunodeficiency syndrome and have received high doses of trimethoprim for the treatment of Pneumocystis carinii pneumonia, trimethoprim causes an increase in P K … WebAug 16, 2016 · Trimethoprim-sulfamethoxazole (TMP-SMX) is a commonly prescribed antibiotic used at high doses for treatment of pneumocystis pneumonia and other infections. Trimethoprim is structurally related to the potassium-sparing diuretic amiloride and has been associated with hyperkalemia and hyponatremia through blocking of …
Trimethoprim-sulfamethoxazole-induced hyponatremia in an... : …
WebMethotrexate. trimethoprim-sulfamethoxazole. deadly drug interaction. folinic acid rescue. pancytopenia. 1. Introduction. Methotrexate (MTX) is a chemotherapeutic synthetic (s) phase cell cycle-specific inhibitor that preferentially targets actively proliferating tissues. It irreversibly binds and inhibits dihydrofolate reductase enzyme and ... WebApr 13, 2024 · You may not have any symptoms at all. But if your potassium levels are high enough to cause symptoms, you may have: tiredness or weakness. a feeling of numbness or tingling. nausea or vomiting ... olgc claim form
Trimethoprim and Potassium-Sparing Drugs: A Risk for …
WebTrimethoprim decreases urinary potassium excretion. May cause hyperkalemia, particularly with high doses, renal insufficiency, or when combined with other drugs that cause hyperkalemia. cannabidiol. cannabidiol will increase the level or effect of trimethoprim by decreasing metabolism. WebOct 14, 2012 · The authors present a case of Trimethoprim-sulfamethoxazole-induced hyperkalemia in a patient with normal renal function. While toxicity of this drug has been reported in patients with renal insufficiency, this case highlights the toxicity associated with normal kidney function. Due to its popularity in the medical field and to the largely … WebJun 18, 2024 · The interaction can lead to dangerously high levels of potassium (hyperkalemia) in the body, which in turn can trigger fatal heart rhythm ... These days, generic forms are dispensed as co-trimoxazole or the combination trimethoprim and sulfamethoxazole (abbreviated TMP-SMX or TMP-SMZ). This combination antibiotic is ... is airband broadband any good