Tmem97 and nash
WebAbcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that … WebJul 11, 2024 · TMEM97 encodes the Sigma-2 receptor which is involved in apoptosis and cytotoxicity across a range of neurodegenerative diseases. However, the expression pattern of TMEM97 in the human retina and ...
Tmem97 and nash
Did you know?
WebFeb 1, 2024 · TMEM97 was recently identified as the gene that codes for the Sigma-2 receptor (26). Sigma-2 receptors have been known for more than four decades and are drug targets for several . perpetuity. It is made available under aCC-BY 4.0 International license. preprint (which was not certified by peer review) is the author/funder, who has granted ... WebMar 28, 2024 · Treatment with the TMEM97 ligand 20-(S)-hydroxycholesterol reduced co-immunoprecipitation of both TMEM97 and PGRMC1 in immune pellets of immunoprecipitated TSPO in MP cells.
WebOverview Product name Anti-TMEM97 antibody Description Rabbit polyclonal to TMEM97 Host species Rabbit Tested applications Suitable for: WB, IHC-P more details Species reactivity Reacts with: Human Immunogen antigen sequence: FEDFSKASGFKGQRPETLHERLT, corresponding to amino acids 120-142 of Human … WebOct 6, 2024 · TMEM97 deficiency also suppressed cell viability, proliferation, colony formation, migration, invasion, and stemness properties in breast cancer cells. …
WebAug 1, 2024 · Previously, the membrane protein TMEM97 has been identified as an NPC1-interacting protein and regulator of cellular cholesterol levels [26].Decreased TMEM97 levels result in enhanced NPC1 protein levels, along with restored cholesterol transport and decreased lipid accumulation in NPC in vitro models [27].Despite these significant … WebAlthough the sigma-2 receptor was identified as a separate pharmacological entity from the sigma-1 receptor in 1990, the gene that codes for the receptor was identified as TMEM97 …
WebDec 6, 2024 · Indeed, some TMEMs such as TMEM48 or TMEM97 are defined as potential prognostic biomarkers for lung cancer. Furthermore, experimental evidence suggests that TMEM proteins can be described as...
WebJan 28, 2024 · TMEM97 has a role in cholesterol and lipid metabolism 10, 11, 12, and it was reported that TMEM97 and cholesterol biosynthesis genes in normal ovarian epithelial cells were coordinately... pershing gold corporation stock quoteWebJul 11, 2024 · TMEM97 encodes the Sigma-2 receptor which is involved in apoptosis and cytotoxicity across a range of neurodegenerative diseases. However, the expression … pershing gold corporationWebThe Pharmacological Profile of TMEM97 Is Identical to That of the σ 2 Receptor. If TMEM97 is indeed the σ 2 receptor, its expression should be required for σ 2 binding activity.To test whether TMEM97 expression contributes to the σ 2 site, we used siRNA knockdown to reduce mRNA expression of Tmem97 by ∼60% in PC-12 cells, a pershing gold scamWebFeb 4, 2024 · As the name suggests, TMEM family is a type of proteins that spans biological membranes including plasma membrane and membrane of organelles. TMEM proteins … stalin cleansingWebTMEM97 is a conserved integral membrane protein that plays a role in controlling cellular cholesterol levels (Bartz et al., 2009 [PubMed 19583955]).[supplied by OMIM, Aug 2009] … pershing general hospital nevadaWebJun 1, 2024 · The expression of TMEM97, a regulator of cholesterol transport, has been reported to be enhanced in some tumour cells. We have recently shown that TMEM97 is … stalin churchillWebTMEM97 Antibodies. Antibodies that detect TMEM97 can be used in several scientific applications, including Immunohistochemistry, Western Blot and Immunocytochemistry. These antibodies target TMEM97 in Human and Mouse samples. Our TMEM97 polyclonal antibodies are developed in Rabbit. Find the TMEM97 antibody that fits your needs. stalin clothes