WebInhibition of Microtubule Assembly HRAC Group 13 (Legacy F4) Inhibition of Microtubule Assembly 2HRAC Group 3 (Legacy K1) ... Inhibition of Enolpyruvyl Shikimate Phosphate Synthase HRAC Group 9 (Legacy G) 112: Lolium rigidum: Rigid Ryegrass: 1034: Overview. Filter Data. Charts. Maps. Mutations. Herbicides. Weeds. WebThe potential of using small-molecule c-Myc inhibitor, 10058-F4, was evaluated on hepatocellular carcinoma cell lines, HepG2 and Hep3B cells. HepG2 cells were more …
HRAC Mode of Action Classification 2024
Web10058-F4. Catalog No.S7153. For research use only. 10058-F4 is a c-Myc inhibitor that specificallly inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression. 10058-F4 promotes a caspase-3-dependent apoptosis and modulates autophagy. CAS No. 403811-55-2. WebThe potential of using small-molecule c-Myc inhibitor, 10058-F4, was evaluated on hepatocellular carcinoma cell lines, HepG2 and Hep3B cells. HepG2 cells were more sensitive to 10058-F4 than Hep3B cells, as demonstrated by reduced cell viability, marked morphological changes and decreased c-Myc levels. 10058-F4 arrested the cell cycle (at … rumah american classic
C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor …
WebJun 2, 2016 · Abstract. Delta-like ligand 4 (Dll4), one of the Notch ligands, is overexpressed in ovarian cancer, especially in tumors resistant to anti-VEGF therapy. Here, we … WebFeb 7, 2024 · Effects of DPP-4 Inhibitors on the Heart. Could DPP-4 inhibitors lead to heart failure by exerting a deleterious effect on the heart? In experimental models, DPP-4 … WebOct 17, 2007 · Using 10058-F4 inhibitor to target MYC-MAX transcription factor, time-dependent and end point questions were posed to answer the mechanism and biological consequence of MYC inhibition in initiating the reversal of dysregulated MYC function. In this part of the study, we determined the regulation of MYC mRNA and several miRNAs … rumah chiffon klaten